Truck on its way to deliver the books trna main idea dna transcription transcription takes place in the nucleus, where genes dna on chromosomes are transcribed into mrna by rna polymerase. Protein synthesis analogy purpose to help students understand the role of dna, mrna, trna and amino acids in the role of protein synthesis translation to reiterate the concept of mutations materials 20 dna template cards 64 trna anticodon cards paperto write down the mrna strand, figure out the trna, and the sentence. Protein synthesis cells biology fuseschool youtube. The nucleolus of the school is the principal because the principal makes the rules just like the nucleolus makes the ribosomes. Rna interference after watching activity teacher notes objective the two analogies in this activity illustrate how rnai interferes with specific gene expression and protein production. Apr 11, 20 an analogy that i have written to help students to understand the basic process for protein synthesis.
The second stage in protein synthesis is the elongation stage, where amino acids are combined to form a polypeptide chain. Rna interference after watching activity teacher notes. They were instructed to map an entire system, meaning that all of the parts of their analogy had to relate to a singular topic. Work with the person next to you to draw a picture of how you think gene expression or protein synthesis works. Protein synthesis analogy project by axel gomez on prezi. Jul 16, 2017 the order of the bases of dna determines which protein is made, by coding for a specific order of amino acids. Pdf gene transcription and translation in design researchgate. While mtorc1 stimulates protein synthesis, it is a major negative regulator of autophagy figure 1. While the rectangle chart is the common format, there may be other. Section of dna with directions to make one protein 6.
In the space below, record the venn diagram you created in the simulation comparing a typical animal cell and plant cell. Structure and function of the cell inclass cell analogy project. It will be collected as a hw and there will be an inclass quiz based on the information. This process is like building a house, with instructions to direct workers. Visual analogy using master plans and blueprints as an analogy for dna and rna helps students comprehend the different roles of these two types of molecules. Understand and demonstrate how start and stop codons effect the synthesis of a protein. Translation converts mrna from transcription into protein polypeptide codon a sequence of 3 rna nucleotides that code for an amino acid there are 20 amino acids in our body amino acid monomer of protein. Rna is generally singlestranded and not doublestranded. Proteinsynthesis analogy imaginethereisahugerecipebookdnainthelibrarynucleus. An analogy is a bead necklace making kit, where there is a selection of beads to choose from. The central dogma of molecular biology is an explanation of the flow of genetic information. Protein synthesis practice problems u20 use the genetic code from class and answer the questions on a piece of notebook paper to be turned in tomorrow filename. The book mrna printcopy of the story into books storyfinal draft chromosomes. Protein synthesis steps flowchart free pdf file sharing.
Students can define a mutation and describe the different effects of different mutations on amino acid sequences. The second analogy illustrates how rnai interferes with the production of a protein. But in eukarytoes, the rna synthesis takes place in the nucleus while the protein synthesis. Protein synthesis involves connecting amino acids into chains beginning at a control center the nucleus of the cell to get a copy of the original plan dna and transcribe that plan into a code that will result in a specific amino acid sequence in a polypeptide chain. How different people have different traits our traits are determined by the kinds of proteins in our bodies dna is a molecule inside each cells nucleus, and is an extremely important molecule because it provides all the. Biology tomorrow belongs to those who prepare today. Oct 22, 2017 i support any analogy that helps you think about this in meaningful ways, so long as you remember the key that an analogy is always good at some points and misleading at others. To access even more information about these materials, you can read our accompanying lesson by the title of protein synthesis analogy. Protein synthesis notes hamilton township high school. From gene to protein genes are stretches of nucleotides organized in triplets different arrangements or dna triplets encode for each one of the 20 amino acids that make proteins during transcription, a dna triplet will produce an mrna codon. If i want to make a cake, i go to her house and copy the recipe. There are hundreds of thousands of types of proteins in living things, but they are all made using a similar process.
Protein synthesis involves connecting amino acids into chains. Additional information reminder cell and cell membrane transport test on monday. But in eukarytoes, the rna synthesis takes place in the nucleus while the protein synthesis takes place in the cytoplasm. Explanation of the central dogma using a musical analogy francis harry compton crick. Protein synthesis takes place on ribosomesenormous complexes containing three large rna molecules and more than 50 proteins. In this modified set up, we calculate the translation rate based on the slowest waiting time, in analogy with the results for the single codon. Go through the process of synthesizing proteins through rna transcription and translation. Willy wonka has recently become a hermit and will not leave his office for much of anything. Follow down the leftmost column labeled first base until you find the letter c. Since there are 22 different amino acids, not all chains are alike.
It include s all occuring reactions from the first peptide bond. Structure and function of the cell inclass cell analogy project directions. You will use then when simulating protein synthesis from mrna. General overview transcription translation mrna leaves the nucleus to the cytoplasm. Every three bases of our secret pseudo protein code codes for a letter or punctuation mark. Circular structure of eukaryotic mrna thought to facilitate rebinding of ribosomes important control point. Protein synthesis reading in the genetics unit so far, we have discussed the following. Dna, the code to make proteins dna the code to make proteins, trapped.
During translation, a codon will constitute an amino acid. Apr 09, 2012 hank imagines himself breaking into the hot pockets factory to steal their secret recipes and instruction manuals in order to help us understand how the processes known as dna transcription and. During this activity you modeled protein synthesis using mrna. You may use diagrams or pictures to supplement your answers, but a diagram or picture alone without appropriate discussion is inadequate. Pdf valuable information on translation initiation is available from biochemical data and. Protein synthesis protein synthesis is the process by which the body manufactures proteins, some of which are enzymes, for use in the body. Protein synthesis analogy by biology buff teachers pay. Gene expression is the process by which information from a gene is used in the synthesis of a. Pdf initiation of protein synthesis in bacteria researchgate.
Other results for rna and protein synthesis gizmo answers pdf. What are the biological equivalents of the blue prints, the construction site, the builders photocopies of the blueprints, the actual building materials, the bobcat loader and the finished building. What would entering the kitchen to make the food item be in relation to protein synthesis by rna. Explore the steps of transcription and translation in protein synthesis. This is a pdf file of an unedited manuscript that has. Protein synthesis uses 3 types of rna three forms of rna involved in protein synthesis 1. Schematic diagram of mismatches in the mapping between protein synthesis and the version. Start studying protein synthesis to bakery analogy. Since our secret pseudo protein code is more familiar, we will use it to examine mutations. The 10 sequential steps of protein synthesis were explained during a lecture discussion format. A ribosome contains 2 subunits attaches to it the ribosome help create amino acids and proteins trna contains amino acids that are used. Rna interference after watching activity teacher notes acting. The product of the entire transcription process that began with the production of the.
Students seem to really like it and understand from. In prokaryotes, the rna synthesis transcription and protein synthesis translation take place in the same compartment as there is no separate nucleus. Click on the appropriate document title below in order to download the file. Lecture notes and handouts accompany campbell biology in focus 2nd edition selection file type icon file name description size revision time user 1 notes. Introduce the candy factory analogy for protein transportstudents come up with their own analogy of the process. Many millions of them may be at work in a cell at any given moment. Before i can make the cake i call the store and have someone deliver the ingredients.
Do it several times, until students are familiar with the sequence. Students seem to really like it and understand from the analogy. Write your own analogy your 1page analogy must include charactersobjects that have similar functions or roles when compared to these major players in the process of protein synthesis. The file below is a webquest on the topic of epigenetics. Synthesis to make dna rna protein protein synthesis occurs in two major parts. Jan 25, 2011 protein synthesis involves connecting amino acids into chains. Protein synthesis practice worksheet teachers pay teachers. A ribosome then reads the mrna and makes a chain of amino acids that will then fold into the specific protein. Protein synthesis practice 2 answers free pdf file sharing.
Students of many ages benefit from analogies, which assist them in understanding, visualizing, and remembering new concepts orgill and bodner, 2007. To show how rnai blocks protein synthesis, have students act out the bread interrupted analogy. Crosstalk between protein synthesis, energy metabolism. Muttt atiiions by analogy every three bases on the mrna codes for an amino acid. Interactive art this animation of transcription and translation helps students make sense of the processes involved in protein synthesis. Analysis of analogy use in secondary education science.
Students can visualize the process of protein synthesis and transport in the cell. Apparently, cooking is an analogy for protein synthesis. School cell analogy the nucleolus is the dark spot in the middle of the nucleus where ribosomes synthesis takes place. Many of the machines built from the blueprints are processors, where the inputs are different from the outputs catalyzing other reactions.
Protein synthesis notes dna to proteins connections. Making a chain of amino acids from mrna is called translation. Protein synthesis u20 study guide the first day thursday, december 11th of the protein synthesis test will be identifying illustrations, fill in the filename. Know where each stage of protein synthesis occurs in the cell. The production of a rna copy from a dna strand is called transcription, and is. Protein synthesis analogy use the illustration to the right help answer the questions 1. All codes in this four by four block begin with the letter c. Nutrient deprivation, which causes mtorc1 inhibition, induces autophagy, thereby supplying the free amino acids needed for the synthesis of crucial proteins. Proteins are composed of amino acids there are 20different amino acids. If you take this seriously, the quiz will be a breeze. Comparing rna and dna each nucleotide in both dna and rna is made up of a 5carbon sugar, a phosphate group, and a nitrogenous base. Pdf inhibition of protein synthesis by streptogramin and related. Secret pseudo protein code the table shows the secret pseudo protein code. Itisforbiddentoremovethebookdnafromthelibrarynucleus.
Ribonucleic acid rna plays an important role in the synthesis of proteins. An analogy between the glutarimide antibiotics and the ipecac alkaloids will be demonstrated in this paper. A ribosome contains 2 subunits attaches to it the ribosome help create amino acids and proteins trna contains amino acids that are used to make proteins mrna is read in three letter codons each codon of mrna matches a anti. Workers make copies of these blueprints, and then use those blueprints to build all sorts of machines and processors. Stepbystep students compare the process of making a cake to the process of making a protein click to see youtube video on how i use this in the classroom with a partner, students compare the process of making a cake to the process of making a protein following a worksheet, while utilizing paper manipulatives. Be sure to detail the roles of dna, mrna, rrna, trna, amino acids and protein. To make an analogy comparison drawing, think of real life situations where. Initiation involves eifs, cap recognition eif4e, and movement to aug start codon eif2. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Put your protein synthesis expertise to the challenge with the assistance of this quizworksheet. Pdf the streptogramins and related antibiotics the lincosamides and macrolides mls are important inhibitors of bacterial protein synthesis. Analogies help students to understand difficult concepts by comparing them to realworld scenarios like making food and building a house. You do need a blueprint to tell you which protein is being built. Current bid publications and practices focus on analogy.
We show here that the matthews equation for protein synthesis is valid if and only if. If this had been an mrna coding for a protein, what would have been changed. Amino acids put these steps of protein synthesis in the correct order. Students follow along with the reading and look at the diagrams on the first page to compare making chili to protein synthesis. Protein synthesis by mrs g classroom teachers pay teachers. Next, students will quiz each other using a page size. Stepbystep students compare the process of making a cake to the process of making a protein click to see youtube video on how i use this in the classroom with a partner, students compare the process of making a cake to the process of making a protein following a worksh. This is protein synthesis, and in this video we are going to look at how it works.
One of the great triumphs in biochemistry in recent years has been the determination of the structure of the ribosome and its components so that its function can be examined in atomic detail figure 29. What do our cells contain that give the instructions for the making of a protein. You do not have to fill out the notes, but you may do so if you like. Given a sequence of dna construct the protein using transcription and translation. There are three important differences between rna and dna. Career scientist of the health research council of the city of new york. My mom has boxes of recipes she wont let out of her house. Picture that you have a library full of blueprints dna.1231 766 490 465 751 1177 1175 98 400 1539 360 1478 313 863 1028 681 1283 1526 546 666 125 1113 595 1492 882 1084 793 1096 941 461 752 660 39